Before he was being politically incorrect, Bill Maher was entertaining granny on not one but two Murder, She Wrote episodes!
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In the first episode, the mulleted Maher actually gets to face off against Ms. Fletcher. In the second episode, which aired just one year later, he played a different character on one of the show's "bookend" episodes in which Ms. Lansbury only appears at the beginning and end of the episode to introduce the night's mystery.