The 1966 Batman television series had a frantic shooting schedule. Its second season ran an amazing 60 episodes, which drained many actors. As a result, a few of the characters were played by multiple actors, including Mr. Freeze, who was played by George Sanders:
Eli Wallach:
And amazingly, even legendary director Otto Preminger:
Though Mr. Preminger did direct the film Skidoo a few years later, so perhaps he wasn't of sound mind at the time.